Amy enthusiastically accepts Sheldon's marriage proposal. However, when dining with Amy's colleagues later that night, Sheldon is offended that they are more impressed with Amy's work than his own. With help from Stephen Hawking, Sheldon later comes to grips with the fact that he will not always be the center of attention in the marriage. Bernadette is shocked to realize that she is pregnant again. She and Howard are not thrilled at the idea of having another baby so soon after their first. They attempt to convince Leonard and Penny to have a child as well, but are rebuffed.
On March 13, 2017, CBS ordered the spin-off Young Sheldon series. Jon Favreau directed and executive produced the pilot. Created by Lorre and Molaro, the series follows 9-year-old Sheldon Cooper as he attends high school in East Texas. Alongside Armitage as 9-year-old Sheldon Cooper and Perry as Mary Cooper, Lance Barber stars as George Cooper, Sheldon's father; Raegan Revord stars as Missy Cooper, Sheldon's twin sister; and Montana Jordan as George Cooper Jr., Sheldon's older brother. Jim Parsons reprises his role as adult Sheldon Cooper, as narrator for the series. Parsons, Lorre, Molaro and Todd Spiewak will also serve as executive producers on the series, for Chuck Lorre Productions, Inc. in association with Warner Bros. Television. The show's pilot episode premiered on September 25, 2017. Subsequent weekly episodes began airing on November 2, 2017 following the broadcast of the 237th episode of The Big Bang Theory.
In the show, the song "Soft Kitty" was described by Sheldon as a song sung by his mother when he was ill. Its repeated use in the series popularized the song. A scene depicting the origin of the song in Sheldon's childhood is depicted in an episode of Young Sheldon, which aired on February 1, 2018. It shows Sheldon's mother Mary singing the song to her son, who is suffering with the flu.
Star Trek in particular is frequently referenced and Sheldon identifies strongly with the character of Spock, so much so that when he is given a used napkin signed by Leonard Nimoy as a Christmas gift from Penny he is overwhelmed with excitement and gratitude ("I possess the DNA of Leonard Nimoy?!"). Star Trek: The Original Series cast member George Takei has made a cameo, and Leonard Nimoy made a cameo as the voice of Sheldon's vintage Mr. Spock action figure (both cameos were in dream sequences). Star Trek: The Next Generation cast members Brent Spiner and LeVar Burton have had cameos as themselves, while Wil Wheaton has a recurring role as a fictionalized version of himself. Leonard and Sheldon have had conversations in the Klingon language.
In the apartment building where Sheldon, Leonard and Penny (and later Amy) live, the elevator has been out of order throughout most of the series, forcing characters to have to use the stairs. Stairway conversations between characters occur in almost every episode, often serving as a transition between longer scenes. The Season 3 episode, "The Staircase Implementation" reveals that the elevator was broken when Leonard was experimenting with rocket fuel. In the penultimate episode of the series, the elevator is returned to an operational state, causing Sheldon some angst.
After Sheldon reminds the guys about the time they mined Bitcoin without him, the guys go on a quest to find their suddenly valuable missing cryptocurrency. They realize the currency is on a laptop which Leonard gave to Penny when they dating, which she then gave to her ex-boyfriend Zack. After Leonard and Penny go to Zack's apartment, he shows them a seven-year-old video that Penny recorded on the laptop soon after she broke up with Leonard. Leonard is touched by the video which shows a drunk Penny lamenting the break-up of her relationship with him.