Amy and Howard begin collaborating on a neuroprosthetics project, upsetting Sheldon and Raj, who feel they are not spending as much time with them. When they seek solace with an annoyed Bernadette, she exploits the situation to trick Sheldon into doing Howard's chores. Penny successfully employs the approaches recommended in one of Bernadette's parenting books to deal with Sheldon, but Leonard believes she is coddling Sheldon too much. Sheldon and Raj resolve the issue of missing their significant others by spending time together.
Wil Wheaton brings William Shatner on his Professor Proton show to meet Sheldon, who gets so excited that he vomits on Shatner. Going to Wil to apologize, he finds Wil hosts a Dungeons & Dragons group with his celebrity friends including Shatner. Finding out Stuart is in the group and never told them, the guys make Stuart panic and quit. Wil secretly invites Leonard who discovers that the group also includes Shatner, Kevin Smith, Joe Manganiello and Kareem Abdul-Jabbar. Leonard tells Penny, who tells Amy and Bernadette, all three women having a crush on Manganiello. Because of that indiscretion, Wil kicks out Leonard and admonishes the guys for using him for his connections, and says that one of the worst things about being a celebrity is not knowing whether someone will like him for himself. To apologize, the guys invite Wil to play D&D with them at Leonard’s apartment, but Wil, secretly in the middle of a game with Penny, Amy and Bernadette and the group, politely turns them down, before allowing the girls to send them a photo of the events as payback.
Mayim Bialik as Amy Farrah Fowler (guest star season 3, starring seasons 4–12):[52] A woman selected by an online dating site as Sheldon's perfect mate.[53] Amy is from Glendale, CA. While she and Sheldon initially share social cluelessness, after befriending Penny and Bernadette she eventually becomes more interested in social and romantic interaction. Her relationship with Sheldon slowly progresses to the point at which Sheldon considers her his girlfriend, eventually they get married. Amy believes she and Penny are best friends, a sentiment that Penny does not initially share. Amy has a Ph.D. in neurobiology.
The sixth season boasts some of the highest-rated episodes for the show so far, with a then-new series high set with "The Bakersfield Expedition", with 20 million viewers,[97] a first for the series, which along with NCIS, made CBS the first network to have two scripted series reach that large an audience in the same week since 2007. In the sixth season, the show became the highest rated and viewed scripted show in the 18–49 demographic, trailing only the live regular NBC Sunday Night Football coverage,[98][99] and was third in total viewers, trailing NCIS and Sunday Night Football.[100] Season seven of the series opened strong, continuing the success gained in season six, with the second episode of the premiere, "The Deception Verification", setting the new series high in viewers with 20.44 million.[101][102]
Although earlier this season Penny (Kaley Cuocuo) told her husband Leonard (Johnny Galecki) that she never wanted kids, part two of the finale reveals that she is pregnant. But when Sheldon dismisses her announcement, Leonard angrily says “to hell with” his Nobel Prize. When his friends threaten to leave at his poor treatment of them, Sheldon takes time to self reflect.
I have watched this program since the beginning. It has very often been zany and unpredictable….tonight it was neither. So everything is “nicey nicey” on the last show, but far from comedy. There have been many memorable comedy series finales …Newhart, Seinfeld, etc……unfortunaely, thus was not one of those and I am sad that a potentially great TV moment was squandered
"The Skank Reflex Analysis" "The Infestation Hypothesis" "The Wiggly Finger Catalyst" "The Russian Rocket Reaction" "The Rhinitis Revelation" "The Good Guy Fluctuation" "The Isolation Permutation" "The Flaming Spittoon Acquisition" "The Shiny Trinket Maneuver" "The Recombination Hypothesis" "The Beta Test Initiation" "The Werewolf Transformation" "The Hawking Excitation" "The Stag Convergence" "The Countdown Reflection"

Simon Helberg doesn't have any projects listed in development as of now, but he has had a burgeoning movie career. He was nominated for a Golden Globe for Florence Foster Jenkins and also appeared in Paint It Black. Maybe he's holding out hope for a spinoff for his Howard Wolowitz? When THR asked creator Chuck Lorre if he was gestating on ideas for any Big Bang character spinoffs, he coyly responded, "You can't help but gestate a little..."
Two nerdy physicists share an apartment and an unlikely friendship with their beautiful neighbor with whom one of them is infatuated. Like the universe after the big bang, the show's popularity expanded, thanks to breakout star Jim Parsons, along with the chemistry among the friends and the developing romance between Leonard and Penny. The addition of Melissa Rauch and Mayim Bialik in later seasons also enhanced the stories and relationships of the leads.

Warner Bros. Television controls the online rights for the show.[159][160] Full episodes are available at tv.com, while short clips and recently aired full episodes are available on cbs.com.[161] In Canada, recent episode(s) and pictures are available on CTV.ca.[162] Additionally in Canada, the first six seasons are available for streaming on Bell Media's CraveTV.[163] After the show has aired in New Zealand the shows are available in full online at TVNZ's on demand web service.
In March 2017, the main cast members (Galecki, Parsons, Cuoco, Helberg, and Nayyar) took a 10% pay cut to allow Bialik and Rauch an increase in their earnings.[40] This put Galecki, Parsons, Cuoco, Helberg and Nayyar at $900,000 per episode, with Parsons, Galecki, and Helberg also receiving overall deals with Warner Bros. Television.[22] By the end of April, Bialik and Rauch had signed deals to earn $500,000 per episode, each, with the deals also including a separate development component for both actors. The deal was an increase from the $175,000 – $200,000 the duo had been making per episode.[41]
By season seven, Galecki, Parsons, and Cuoco were also receiving 0.25% of the series' back-end money. Before production began on the eighth season, the three plus Helberg and Nayyar, looked to renegotiate new contracts, with Galecki, Parsons, and Cuoco seeking around $1 million per episode, as well as more back-end money.[36] Contracts were signed in the beginning of August 2014, giving the three principal actors an estimated $1 million per episode for three years, with the possibility to extend for a fourth year. The deals also include larger pieces of the show, signing bonuses, production deals, and advances towards the back-end.[37] Helberg and Nayyar were also able to renegotiate their contracts, giving them a per-episode pay in the "mid-six-figure range", up from around $100,000 per episode they each received in years prior. The duo, who were looking to have salary parity with Parsons, Galecki, and Cuoco, signed their contracts after the studio and producers threatened to write the characters out of the series if a deal could not be reached before the start of production on season eight.[38] By season 10, Helberg and Nayyar reached the $1 million per episode parity with Parsons, Galecki, and Cuoco, due to a clause in their deals signed in 2014.[39]
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