In scenes set at Howard's home, he interacts with his rarely-seen mother (voiced by Carol Ann Susi until her death) by shouting from room to room in the house. She similarly interacts with other characters in this manner.[85] She reflects the Jewish mother stereotype in some ways, such as being overly controlling of Howard's adult life and sometimes trying to make him feel guilty about causing her trouble. She is dependent on Howard, as she requires him to help her with her wig and makeup in the morning. Howard, in turn, is attached to his mother to the point where she still cuts his meat for him, takes him to the dentist, does his laundry and "grounds" him when he returns home after briefly moving out.[86] Until Howard's marriage to Bernadette in the fifth-season finale, Howard's former living situation led Leonard's psychiatrist mother to speculate that he may suffer from some type of pathology,[87] and Sheldon to refer to their relationship as Oedipal.[88] In season 8, Howard's mother dies in her sleep while in Florida, which devastates Howard and Stuart, who briefly lived with Mrs. Wolowitz.
Johnny Galecki as Leonard Hofstadter:[42] An experimental physicist with an IQ of 173, who received his PhD when he was 24 years old. Leonard is a nerd who loves video games, comic books, and Dungeons & Dragons. Leonard is the straight man of the series, in which he shares an apartment in Pasadena, CA, with Sheldon. Leonard is smitten with his new neighbor Penny when they first meet, and they eventually marry.
The episode opens with a short montage of clips from the series' twelve seasons, then segues to Sheldon and Amy, who are up late waiting for a call from the Nobel Committee. Following a prank call from Kripke, they are told they've won the Nobel Prize in Physics for their super-asymmetry work. The attention from the media and the university bothers Sheldon. Amy is saddened by an unflattering picture of her in a news report, so Raj convinces her to get a makeover. She loves her new look but Sheldon demands she change it back. Leonard calls him out for being rude, but Sheldon flees when he sees Penny emerge from the newly repaired elevator. Sheldon and Penny go to the Cheesecake Factory and Penny tells Sheldon that change is the only constant thing in life. On a TV, they see Bernadette and Howard take credit as Sheldon and Amy's best friends. Raj and Leonard defend Amy, with Leonard accidentally breaking Sheldon's DNA molecule model in Apartment 4A. Penny convinces Sheldon to ride in the elevator.

Cosmologist Stephen Hawking made a short guest appearance in the fifth-season episode;[57] in the eighth season, Hawking video conferences with Sheldon and Leonard, and makes another appearance in the 200th episode. In the fifth and sixth seasons, NASA astronaut Michael J. Massimino played himself multiple times in the role of Howard's fellow astronaut. Bill Nye appeared in the seventh and twelfth seasons.
Filming proceeds smoothly – makeup artists do touch-ups, a prop master replenishes the pickle supply – with humor and camaraderie between takes. When a reshoot is needed because Simon Helberg, who plays Howard, held his napkin in the wrong hand, Kaley Cuoco, who plays Penny, lifts her food box high and mockingly asks, “Does it go over my head? I don’t remember.”

Howard dresses as Sheldon for Halloween at work, hurting Sheldon's feelings. When Howard does not apologize, Amy and Sheldon dress as Bernadette and Howard at Penny and Leonard's party, angering Bernadette. Sheldon and Bernadette later bond over their painful childhood memories. Leonard is upset that Penny does not seem to remember that their first kiss was on Halloween. Penny later admits she does remember, but does not like to think of their first kiss as an unromantic drunken hookup. She likes to imagine their first kiss was one they shared on Leonard's birthday, which pleases him.


While opening their wedding gifts, Sheldon and Amy cannot figure out the purpose of the glass shard Leonard and Penny gave them. They decide it must be a clue to a scavenger hunt to the real gift. They eventually end up in the coffee shop where they first met and find a locket in the lost and found that they think must be the real gift. The glass shard was actually a crystal chakra wand that Raj gave as a gift to Howard and Bernadette, who then re-gifted it to Leonard and Penny, who finally passed it on as a joke. Leonard and Penny find it less funny when they are given a coded thank-you note they have to use to unlock their WiFi. After making out with his employee Denise at Sheldon and Amy's wedding reception, Stuart finally asks Denise out on a date; while preparing for the date, he has a spray-tan accident, but she just finds it funny and still goes out with him. Raj is depressed everyone else has a relationship and asks his father to arrange a marriage.
I love the show and cant believe it is done. I feel that that final episode left me wanting more. It did answer alot of questions that where asked about the show but I feel that it also made more come up that wont be answered.i hope that there will be a spin off to the series with the crew that wants to just because jim parson wants to move on to other things i hope it doesnt stop the rest of them to stop.
^ From the eighth season onward, episodes of each season initially aired on Monday nights, before later returning to the Thursday night slot for the rest of the season. The eighth and ninth seasons returned on the seventh episode,[126][127] the tenth and eleventh seasons on the sixth episode,[128][129] and the twelfth season on the second episode.[130]

Professor Proton, Sheldon's favorite childhood show, is being rebooted. After unsuccessfully auditioning for the part, he goes to Wil Wheaton for acting tips for his second audition. However, Sheldon is later dismayed when Wil is offered the role instead. Talking it over with Arthur in his dreams, he is still upset to see his idol replaced and considers Wil an enemy again. Meanwhile, Howard gets a vasectomy while Bernadette is on bed rest. Penny offers to take care of Halley for them, but they insult her by expecting her to be irresponsible. Halley ends up saying her first word by calling Penny "Mama."


Kunal Nayyar as Rajesh Koothrappali:[46] A particle astrophysicist originally from New Delhi, India. Raj is initially unable to talk to women unless he drinks alcohol. Raj also has very feminine tastes and often takes on a stereotypical female role in his friendship with Howard as well as in the group of four men. Raj later dates Lucy (Kate Micucci), who also suffers from social anxiety, but it eventually ends; he later speaks to Penny without alcohol and thus overcomes his selective mutism. He begins dating Emily and their relationship later becomes exclusive. Raj also has a Yorkshire Terrier named Cinnamon.
As the theme of the show revolves around science, many distinguished and high-profile scientists have appeared as guest stars on the show. Famous astrophysicist and Nobel laureate George Smoot had a cameo appearance in the second season.[56] Theoretical physicist Brian Greene appeared in the fourth season, as well as astrophysicist, science populizer, and physics outreach specialist Neil deGrasse Tyson, who also appeared in the twelfth season.
Melissa Rauch as Bernadette Rostenkowski-Wolowitz (recurring season 3, starring seasons 4–12):[51] A young woman who initially is a co-worker at The Cheesecake Factory with Penny to pay her way through graduate school, where she is studying microbiology. Bernadette is introduced to Howard by Penny; at first, they do not get along, apparently having nothing in common. They date and later get engaged and married. Although generally a sweet and good-natured person, Bernadette has a short fuse and can be vindictive and lash out when provoked.
"The Plagiarism Schism" -- Pictured: Howard Wolowitz (Simon Helberg) and Bernadette (Melissa Rauch). Kripke (John Ross Bowie) has proof that Dr. Pemberton (Sean Astin) plagiarized his thesis in college, and Sheldon and Amy aren\'t sure if they should turn him in or not. Also, Wolowitz is happily surprised to learn that Bernadette wasn\'t the only waitress at the Cheesecake Factory who had a crush on him back in the day, on THE BIG BANG THEORY, Thursday, May 2 (8:00-8:31 PM, ET/PT) on the CBS Television Network. Photo: Michael Yarish/Warner Bros. Entertainment Inc. © 2019 WBEI. All rights reserved. (Photo: Michael Yarish, Warner Bros.)
Sheldon and Amy recruit Leonard to research and write citations for their paper on super asymmetry. While working in the campus library, Leonard and Raj discover a Russian paper that asserts that super asymmetry has no merit. Reluctantly, Leonard shares the news with Sheldon and Amy, who fall into a depressive state and do not leave their apartment. Meanwhile, Bernadette asks Denise to teach her how to play Fortnite: Battle Royale so that she can beat Howard. Despite losing to Howard in a rematch after all of her training, Bernadette revels in beating a disinterested Penny.
In November 2016, it was reported that CBS was in negotiations to create a spin-off of The Big Bang Theory centered on Sheldon as a young boy. The prequel series, described as "a Malcolm in the Middle-esque single-camera family comedy" would be executive-produced by Lorre and Molaro, with Prady expected to be involved in some capacity, and intended to air in the 2017–18 season alongside The Big Bang Theory.[211][212] The initial idea for the series came from Parsons, who passed it along to The Big Bang Theory producers.[213] In early March 2017, Iain Armitage was cast as the younger Sheldon, as well as Zoe Perry as his mother, Mary Cooper. Perry is the real-life daughter of Laurie Metcalf, who portrays Mary Cooper on The Big Bang Theory.[213]
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