Science has also interfered with the characters' romantic lives. Leslie breaks up with Leonard when he sides with Sheldon in his support for string theory rather than loop quantum gravity.[70] When Leonard joins Sheldon, Raj, and Howard on a three-month Arctic research trip, it separates Leonard and Penny at a time when their relationship is budding. When Bernadette takes an interest in Leonard's work, it makes both Penny and Howard envious and results in Howard confronting Leonard, and Penny asking Sheldon to teach her physics.[71] Sheldon and Amy also briefly end their relationship after an argument over which of their fields is superior.[72]


Science has also interfered with the characters' romantic lives. Leslie breaks up with Leonard when he sides with Sheldon in his support for string theory rather than loop quantum gravity.[70] When Leonard joins Sheldon, Raj, and Howard on a three-month Arctic research trip, it separates Leonard and Penny at a time when their relationship is budding. When Bernadette takes an interest in Leonard's work, it makes both Penny and Howard envious and results in Howard confronting Leonard, and Penny asking Sheldon to teach her physics.[71] Sheldon and Amy also briefly end their relationship after an argument over which of their fields is superior.[72]
Mayim Bialik as Amy Farrah Fowler (guest star season 3, starring seasons 4–12):[52] A woman selected by an online dating site as Sheldon's perfect mate.[53] Amy is from Glendale, CA. While she and Sheldon initially share social cluelessness, after befriending Penny and Bernadette she eventually becomes more interested in social and romantic interaction. Her relationship with Sheldon slowly progresses to the point at which Sheldon considers her his girlfriend, eventually they get married. Amy believes she and Penny are best friends, a sentiment that Penny does not initially share. Amy has a Ph.D. in neurobiology.
After Neil Gaiman tweets about Stuart's comic book store, it becomes very popular, and the crowds upset Sheldon. Stuart hires an assistant manager named Denise and she impresses Sheldon with her comic recommendations. Amy goes to her for information on comics to connect to Sheldon but when she tries to tell him, he says he's talked enough about comics with Denise. The store's popularity causes Stuart to be unable to babysit for Howard and Bernadette's date night. They try to have another at home, but Stuart shows up so they hurriedly go out. Meanwhile, as Raj sets up a telescope, Penny sees a new comet. Raj takes sole credit for the discovery, angering Penny. Leonard tries to defend her but feels sorry for hurting Raj's career. Penny confronts Raj herself and he agrees to share credit after Penny doesn't give in like Leonard.

The CBS sitcom said goodbye on Thursday night after a storied 12-season run — and now that it’s really over, we’re feeling super nostalgic. Having already revisited the pilot episode, highlighted classic “Shamy” moments and ranked our favorite recurring characters, we’re closing out our retrospective coverage with a list of the 10 episodes that we feel are a cut above the rest.

When Mayim Bialik first learned she had to say goodbye to neurobiologist Amy Farrah Fowler, she opened up about the show ending in a blog post, asking, "And now I start to figure out what next. Where will life take me? Where will this career go? What do I want?" Up next she has a voice role in The Inspector Chronicles, a quasi-parody of Doctor Who making the leap from short to feature film. She'll reprise her role as the voice of the Inspector's time machine, known as B.O.O.T.H. Aside from that, she doesn't have any major projects lined up, aside from preparing to not see her close-knit cast the way she'd grown accustomed to. "We'll have to see what our lives look like," she told Us Weekly in early May about the chance they'll remain close. "I mean, we're all going to be on different schedules now; it's very different."
Kunal Nayyar has the flick Think Like a Dog in post-production and the upcoming Trolls World Tour in pre-production. Nayyar provides the voice of Guy Diamond in the movie series. Aside from that, however, the former Raj Koothrappali is looking forward to some much needed family time. "I'm going to go to India, spend more time with my parents," he told Parade in late April. "I left my country when I was 18, so it's important for me to go home and spend time with mom and dad, so that's the main focus right now.
Penny runs into her ex-boyfriend Zack, who has gotten rich from selling his company and married a similarly dim-witted woman named Marissa. Meeting with Leonard and Penny, they say Zack is infertile and ask to pay Leonard as a sperm donor so they can have a baby. Leonard is flattered, but Penny finds it creepy. Leonard says that since Penny decided she did not want to have children, he should be allowed to help another couple with this issue. Sheldon advises him to think about the emotional toll this could have on him. Leonard says he will not do it if Penny objects; Penny says she will support whatever decision Leonard makes. Meanwhile, Raj tries to get Anu back but she points out he just wanted to be married like his friends. Raj points out that Anu is similarly looking for a quick marriage. He admits to Anu that he really likes her and they decide to start their relationship as just dating.
Two nerdy physicists share an apartment and an unlikely friendship with their beautiful neighbor with whom one of them is infatuated. Like the universe after the big bang, the show's popularity expanded, thanks to breakout star Jim Parsons, along with the chemistry among the friends and the developing romance between Leonard and Penny. The addition of Melissa Rauch and Mayim Bialik in later seasons also enhanced the stories and relationships of the leads.

With all due respect to all of the Sheldon’s out there who can cite episode titles, describing the episode is a LOT more helpful that calling it out by name. I can quote my favorite line/scene from your post (Are they bouncing more than usual,) but “Mike’s” post above is a lot less memory provoking. What was “The Donation Oscillation” about? I can extrapolate MOST of the episodes from the title, but not all. Kudos to those with memories like Sheldon’s, but my bet is far fewer fans can describe an episode by season and title than they can by “The one where James Earl Jones and Sheldon ding dong ditch Carrie Fisher.” :)

After Neil Gaiman tweets about Stuart's comic book store, it becomes very popular, and the crowds upset Sheldon. Stuart hires an assistant manager named Denise and she impresses Sheldon with her comic recommendations. Amy goes to her for information on comics to connect to Sheldon but when she tries to tell him, he says he's talked enough about comics with Denise. The store's popularity causes Stuart to be unable to babysit for Howard and Bernadette's date night. They try to have another at home, but Stuart shows up so they hurriedly go out. Meanwhile, as Raj sets up a telescope, Penny sees a new comet. Raj takes sole credit for the discovery, angering Penny. Leonard tries to defend her but feels sorry for hurting Raj's career. Penny confronts Raj herself and he agrees to share credit after Penny doesn't give in like Leonard.
Two months after the events of "The Change Constant", Sheldon and Leonard repair Sheldon's DNA molecule model as everyone prepares to fly to Sweden for the Nobel Prize award ceremony. Howard and Bernadette nervously leave their kids for the first time with Stuart and Denise, while Raj leaves his dog with Bert. Penny has become pregnant, though she and Leonard are keeping it a secret. On the flight, Raj thinks he spots Sarah Michelle Gellar. Penny's frequent bathroom trips make Sheldon fear she is sick. Leonard reveals the pregnancy to Sheldon, but instead of being excited for Penny, Sheldon is only selfishly relieved that he will not get sick and he exposes the pregnancy, offending Leonard. At the hotel, a series of minor incidents with their kids make Howard and Bernadette want to go home. Much to their dismay, Sheldon is still insensitive. Amy furiously tells Sheldon he broke their friends' hearts and they only tolerate him because he does not intentionally do so, which she also sometimes does. Everyone decides to stay for the ceremony and Raj brings Gellar. After they are awarded their medals, Amy encourages girls to pursue science while Sheldon thanks his family and then individually acknowledges each of his friends and Amy as his other family who always support him. The episode closes with the gang eating in Apartment 4A (an allusion to the final scene in the opening credits) as an acoustic version of the theme song's chorus plays.
After the birth of Michael, Howard and Bernadette are unsure who should stay home with the kids. Howard decides to look after the kids one day to show he has what it takes to care for them. While Bernadette falls back in love with her job on a trip to the office, Howard is quickly tired and realizes he might not have what it takes to be a stay-at-home dad. Howard and Bernadette realize neither them is ready to give up their job.

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While Jim Parsons was the one who'd had enough with The Big Bang Theory, opting not to renew his contract to play socially awkward theoretical physicist Sheldon Cooper and bringing about the demise of the show in the process, he won't be escaping the show's orbit entirely. He's still attached as both executive producer and narrator of prequel series Young Sheldon, returning for a third season on CBS this fall. "There was no factor; there was no situation that I was like, 'Well, I've had enough of that.' No. There was nothing like that. It was just…when you know, you know," he explained to The Hollywood Reporter in mid-May. 
Laura Spencer as Emily Sweeney (recurring seasons 7–8, 10, starring season 9):[55] A dermatologist at Huntington Hospital. Emily went to Harvard and delights in the macabre and states that she likes her job because she can cut things with knives. Prior to meeting Raj, Emily was set up on a blind date with Howard. After finding Emily's online dating profile, Raj has Amy contact her as his wingman instead. Their relationship becomes exclusive, but Raj later breaks up with Emily when he becomes infatuated with the bartender Claire (Alessandra Torresani).
Raj meets with the woman his father set up for him, Anu. Her commanding personality and practical approach to marriage startle Raj but he agrees to go ahead with it. Howard criticizes him but apologizes; he just never expected Raj to give up on romance. Raj admits this to Anu so she proposes to him, and he says yes. Raj also sends out a relationship questionnaire to Leonard and Penny, which soon reveals that Penny does not think she ever wants kids, upsetting Leonard, who would like to have kids someday, and their friends selfishly badger them on the issue. After telling her father Wyatt who is also upset, Leonard tells Penny that he'll be okay with it, as he never thought he'd have her in his life. To get his mind off of it, Penny rents Leonard a Batmobile to drive in and have fun with for the day. Meanwhile, Stuart starts bringing home Denise at night, which is very uncomfortable for Howard and Bernadette. When they also try to have time to themselves, they wake up their kids.
It was really hard to pick the right pic for this post, so here is a shot of us in a hug after we filmed the last group scene we would ever film for the series... and TONIGHT is THE NIGHT... it’s the series finale at 8pm EST and then there’s the Young Sheldon (season!) finale, and then a special behind the scenes show hosted by @kaleycuoco and @sanctionedjohnnygalecki and then the entire cast is on @colbertlateshow I hope you get a chance to tune in and i hope you enjoy all of it. If you enjoy it even half as much as we’ve enjoyed (LOVED) creating this show for the past 12 years, then that’ll be a WHOLE WHOLE lot of enjoyment. All of us will miss seeing you in this format, but we will be around in all sorts of ways, I assure you... love love love ❤️❤️❤️
Sheldon and Amy go on their honeymoon to New York City, starting with Legoland New York. Sheldon's insistence on scheduling their marital relations stresses Amy. He says he only does it to remind himself to be intimate with her. They compromise by letting him make a schedule without sharing it with her. Leonard and Penny discover Mr. Larry Fowler (Teller) in Sheldon and Amy's apartment hiding from his wife (Kathy Bates). Leonard notices parallels in his own marriage, which offends Penny. Leonard apologizes, and Penny convinces Mrs. Fowler to give her husband a break. When Mrs. Fowler wants to hang out with her regularly, Penny scares Larry out of the building. Raj instigates a Twitter feud with Neil deGrasse Tyson but is scared off when confronted over the phone. Neil then calls Bill Nye to scare him, too.
For the first three seasons, Galecki, Parsons, and Cuoco, the three main stars of the show, received at most $60,000 per episode. The salary for the three went up to $200,000 per episode for the fourth season. Their per-episode pay went up an additional $50,000 in each of the following three seasons, culminating in $350,000 per episode in the seventh season.[33][34] In September 2013, Bialik and Rauch renegotiated the contracts they held since they were introduced to the series in 2010. On their old contracts, each was making $20,000–$30,000 per episode, while the new contracts doubled that, beginning at $60,000 per episode, increasing steadily to $100,000 per episode by the end of the contract, as well as adding another year for both.[35]
Sheldon is annoyed that Amy does not have time to work on the super-asymmetry project with him so he talks President Siebert into getting her removed from her own project at the university. Amy is angry at both of them as she wants to still have her own identity outside the marriage. When confronted by Amy, Siebert apologizes to her but states that it will be difficult for the university to give her her project back. After talking with Arthur Jeffries in a dream, Sheldon apologizes to Amy and both of them talk about their fears in their marriage. Meanwhile, Raj does not want to have Howard join him in his show at the planetarium, thinking he'd just use his astronaut status to make it about himself. Raj eventually lets him join in and Raj and Howard spend the whole time complimenting each other, surprising Bernadette, Leonard and Penny.
In the apartment building where Sheldon, Leonard and Penny (and later Amy) live, the elevator has been out of order throughout most of the series, forcing characters to have to use the stairs. Stairway conversations between characters occur in almost every episode, often serving as a transition between longer scenes. The Season 3 episode, "The Staircase Implementation" reveals that the elevator was broken when Leonard was experimenting with rocket fuel.[89] In the penultimate episode of the series, the elevator is returned to an operational state, causing Sheldon some angst.
In scenes set at Howard's home, he interacts with his rarely-seen mother (voiced by Carol Ann Susi until her death) by shouting from room to room in the house. She similarly interacts with other characters in this manner.[85] She reflects the Jewish mother stereotype in some ways, such as being overly controlling of Howard's adult life and sometimes trying to make him feel guilty about causing her trouble. She is dependent on Howard, as she requires him to help her with her wig and makeup in the morning. Howard, in turn, is attached to his mother to the point where she still cuts his meat for him, takes him to the dentist, does his laundry and "grounds" him when he returns home after briefly moving out.[86] Until Howard's marriage to Bernadette in the fifth-season finale, Howard's former living situation led Leonard's psychiatrist mother to speculate that he may suffer from some type of pathology,[87] and Sheldon to refer to their relationship as Oedipal.[88] In season 8, Howard's mother dies in her sleep while in Florida, which devastates Howard and Stuart, who briefly lived with Mrs. Wolowitz.
Professor Proton, Sheldon's favorite childhood show, is being rebooted. After unsuccessfully auditioning for the part, he goes to Wil Wheaton for acting tips for his second audition. However, Sheldon is later dismayed when Wil is offered the role instead. Talking it over with Arthur in his dreams, he is still upset to see his idol replaced and considers Wil an enemy again. Meanwhile, Howard gets a vasectomy while Bernadette is on bed rest. Penny offers to take care of Halley for them, but they insult her by expecting her to be irresponsible. Halley ends up saying her first word by calling Penny "Mama."

Sheldon needs half a billion dollars to prove his latest concept of string theory, which the University cannot afford to fund. Crowdfunding and selling some of his most valuable comic books to Stuart give him a small start. When Raj mentions gambling in Las Vegas, Sheldon goes there but is caught calculating odds by security before he can make any bets. Meanwhile, Amy takes Penny and Bernadette shopping for her wedding dress. She loves an old-fashioned one that the other girls admit that they find ugly, though Penny assures Amy she can make her own decisions about her wedding. Sheldon, however, comes home and sees Amy in the dress and loves how she looks.
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