Sheldon and Amy decide on a wedding date of May 12th. They want to have their reception at the Athenaeum at Caltech. While scouting the location, they are shocked to see Leonard and Penny eating there, as Leonard had told Sheldon their application had been denied. In reality, Leonard just wanted a place to avoid Sheldon. Kripke has booked the venue for his birthday party on the same day as the wedding. Leonard cleans radioactive sludge for Kripke to get the date for Sheldon as an apology for lying. Kripke eventually agrees to change the day but when Amy hears he wants to sing at the wedding, she suggests they get married at the Griffith Observatory instead. Meanwhile, Bernadette and Howard are unsure if one of them should quit their job to stay home with the children. Howard volunteers, but when left alone with the children he passes out exhausted, leaving Raj in charge. When Bernadette meets Penny for lunch, she realizes that she loves being at the office again, but doesn't want to leave the children. She and Howard promise to figure it out later after they take a nap.
Producers, writers and others, including recurring guest star Wil Wheaton, joined the festivities on set and — hardly a spoiler alert — more laughing, crying and hugging ensued. Lorre embraced a happy Parsons, then moved on to each cast member as if it were a reception line. Galecki shared long, emotional hugs with his colleagues. After trying to keep their emotions under control for so long, it was finally time to just let go.
Sheldon cannot find the perfect wedding date and begins talking in his sleep, adopting the persona of a laid-back person who goes with the flow. Amy and Penny believe that his subconscious mind is trying to tell him to be more relaxed; his attempt to be so while wearing flip-flops ends in disaster. He decides to leave all the wedding planning to Amy while he wears a Star Trek uniform underneath his tuxedo. Meanwhile, Raj and Stuart both become interested in Bernadette's new coworker Ruchi. While she likes them both as friends, she does not want a relationship with anyone.
Science has also interfered with the characters' romantic lives. Leslie breaks up with Leonard when he sides with Sheldon in his support for string theory rather than loop quantum gravity. When Leonard joins Sheldon, Raj, and Howard on a three-month Arctic research trip, it separates Leonard and Penny at a time when their relationship is budding. When Bernadette takes an interest in Leonard's work, it makes both Penny and Howard envious and results in Howard confronting Leonard, and Penny asking Sheldon to teach her physics. Sheldon and Amy also briefly end their relationship after an argument over which of their fields is superior.
Raj meets with the woman his father set up for him, Anu. Her commanding personality and practical approach to marriage startle Raj but he agrees to go ahead with it. Howard criticizes him but apologizes; he just never expected Raj to give up on romance. Raj admits this to Anu so she proposes to him, and he says yes. Raj also sends out a relationship questionnaire to Leonard and Penny, which soon reveals that Penny does not think she ever wants kids, upsetting Leonard, who would like to have kids someday, and their friends selfishly badger them on the issue. After telling her father Wyatt who is also upset, Leonard tells Penny that he'll be okay with it, as he never thought he'd have her in his life. To get his mind off of it, Penny rents Leonard a Batmobile to drive in and have fun with for the day. Meanwhile, Stuart starts bringing home Denise at night, which is very uncomfortable for Howard and Bernadette. When they also try to have time to themselves, they wake up their kids.
The CBS sitcom said goodbye on Thursday night after a storied 12-season run — and now that it’s really over, we’re feeling super nostalgic. Having already revisited the pilot episode, highlighted classic “Shamy” moments and ranked our favorite recurring characters, we’re closing out our retrospective coverage with a list of the 10 episodes that we feel are a cut above the rest.
Professor Proton, Sheldon's favorite childhood show, is being rebooted. After unsuccessfully auditioning for the part, he goes to Wil Wheaton for acting tips for his second audition. However, Sheldon is later dismayed when Wil is offered the role instead. Talking it over with Arthur in his dreams, he is still upset to see his idol replaced and considers Wil an enemy again. Meanwhile, Howard gets a vasectomy while Bernadette is on bed rest. Penny offers to take care of Halley for them, but they insult her by expecting her to be irresponsible. Halley ends up saying her first word by calling Penny "Mama."
"The Skank Reflex Analysis" "The Infestation Hypothesis" "The Wiggly Finger Catalyst" "The Russian Rocket Reaction" "The Rhinitis Revelation" "The Good Guy Fluctuation" "The Isolation Permutation" "The Flaming Spittoon Acquisition" "The Shiny Trinket Maneuver" "The Recombination Hypothesis" "The Beta Test Initiation" "The Werewolf Transformation" "The Hawking Excitation" "The Stag Convergence" "The Countdown Reflection"
When Bernadette tells Howard that she is expecting again, he is once again floored with fear about raising another child, particularly when he learns it’s a boy. Howard, who isn't athletically inclined, worries he will not be able to relate to a son who might one day expect his dad to be the stereotypical father. Despite his best attempts to get out of it, Howard has a vasectomy to avoid any future surprises and is placed on bed rest, joining his pregnant wife at home.
Sheldon needs half a billion dollars to prove his latest concept of string theory, which the University cannot afford to fund. Crowdfunding and selling some of his most valuable comic books to Stuart give him a small start. When Raj mentions gambling in Las Vegas, Sheldon goes there but is caught calculating odds by security before he can make any bets. Meanwhile, Amy takes Penny and Bernadette shopping for her wedding dress. She loves an old-fashioned one that the other girls admit that they find ugly, though Penny assures Amy she can make her own decisions about her wedding. Sheldon, however, comes home and sees Amy in the dress and loves how she looks.