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“The Big Bang Theory” premiered on Sept. 24, 2007, and for most of its run, was primetime’s most-watched comedy series. It remains one of the most successful sitcoms in TV history — and the longest-running multi-cam comedy of all time (recently surpassing “Cheers”). It has generated an estimated $1 billion and counting in syndication. The show has received 52 Emmy Award nominations and 10 wins, seven Golden Globe nominations, and the spinoff prequel, “Young Sheldon.”
As the theme of the show revolves around science, many distinguished and high-profile scientists have appeared as guest stars on the show. Famous astrophysicist and Nobel laureate George Smoot had a cameo appearance in the second season. Theoretical physicist Brian Greene appeared in the fourth season, as well as astrophysicist, science populizer, and physics outreach specialist Neil deGrasse Tyson, who also appeared in the twelfth season.
Science has also interfered with the characters' romantic lives. Leslie breaks up with Leonard when he sides with Sheldon in his support for string theory rather than loop quantum gravity. When Leonard joins Sheldon, Raj, and Howard on a three-month Arctic research trip, it separates Leonard and Penny at a time when their relationship is budding. When Bernadette takes an interest in Leonard's work, it makes both Penny and Howard envious and results in Howard confronting Leonard, and Penny asking Sheldon to teach her physics. Sheldon and Amy also briefly end their relationship after an argument over which of their fields is superior.
Howard dresses as Sheldon for Halloween at work, hurting Sheldon's feelings. When Howard does not apologize, Amy and Sheldon dress as Bernadette and Howard at Penny and Leonard's party, angering Bernadette. Sheldon and Bernadette later bond over their painful childhood memories. Leonard is upset that Penny does not seem to remember that their first kiss was on Halloween. Penny later admits she does remember, but does not like to think of their first kiss as an unromantic drunken hookup. She likes to imagine their first kiss was one they shared on Leonard's birthday, which pleases him.
After the strike ended, the show was picked up for a second season, airing in the 2008–2009 season, premiering in the same time slot on September 22, 2008. With increasing ratings, the show received a two-year renewal through the 2010–11 season in 2009. In 2011, the show was picked up for three more seasons. In March 2014, the show was renewed again for three more years through the 2016–17 season. This marked the second time the series gained a three-year renewal. In March 2017, the series was renewed for two additional seasons, bringing its total to 12, and running through the 2018–19 television season.
Sheldon is annoyed that Amy does not have time to work on the super-asymmetry project with him so he talks President Siebert into getting her removed from her own project at the university. Amy is angry at both of them as she wants to still have her own identity outside the marriage. When confronted by Amy, Siebert apologizes to her but states that it will be difficult for the university to give her her project back. After talking with Arthur Jeffries in a dream, Sheldon apologizes to Amy and both of them talk about their fears in their marriage. Meanwhile, Raj does not want to have Howard join him in his show at the planetarium, thinking he'd just use his astronaut status to make it about himself. Raj eventually lets him join in and Raj and Howard spend the whole time complimenting each other, surprising Bernadette, Leonard and Penny.
When Amy sees Sheldon obsessively tying and untying his bow tie the day before their wedding, Amy tells him it doesn't need to be even because sometimes a little asymmetry looks good. On the day of the wedding, Sheldon stops his mother from trying to straighten his bow tie, saying it's supposed to be a little asymmetrical. When Mary comments that sometimes it’s the imperfect stuff that makes things perfect, Sheldon has a flash of inspiration and rushes to see Amy. Sheldon and Amy’s wedding is delayed as they excitedly work on a new theory of “super asymmetry”.
Initial reception for the series was mixed. The review aggregation website Rotten Tomatoes reported a 52% approval rating for the first season based on reviews from 23 critics, with an average rating of 5.18/10. The website's critical consensus reads, "The Big Bang Theory brings a new class of character to mainstream television, but much of the comedy feels formulaic and stiff." On Metacritic, the season holds a score of 57 out of 100, based on reviews from 23 critics, indicating "mixed or average reviews". Later seasons received more acclaim and in 2013, TV Guide ranked the series #52 on its list of the 60 Best Series of All Time.
However, no legal action was required to end production of the other show: as soon as it became known that the show was unlicensed, the actors quit and the producers canceled it. Dmitriy Tankovich (who plays Leonard's counterpart, "Seva") said in an interview, "I'm upset. At first, the actors were told all legal issues were resolved. We didn't know it wasn't the case, so when the creators of The Big Bang Theory started talking about the show, I was embarrassed. I can't understand why our people first do, and then think. I consider this to be the rock bottom of my career. And I don't want to take part in a stolen show".