Mayim Bialik as Amy Farrah Fowler (guest star season 3, starring seasons 4–12):[52] A woman selected by an online dating site as Sheldon's perfect mate.[53] Amy is from Glendale, CA. While she and Sheldon initially share social cluelessness, after befriending Penny and Bernadette she eventually becomes more interested in social and romantic interaction. Her relationship with Sheldon slowly progresses to the point at which Sheldon considers her his girlfriend, eventually they get married. Amy believes she and Penny are best friends, a sentiment that Penny does not initially share. Amy has a Ph.D. in neurobiology.

The Big Bang Theory premiered in the United States on September 24, 2007 on CBS. The series debuted in Canada on CTV in September 2007.[152] On February 14, 2008, the series debuted in the United Kingdom on channels E4 and Channel 4.[153] In Australia the first seven seasons of the series began airing on the Seven Network and 7mate from October 2015 and also gained the rights to season 8 in 2016, though the Nine Network has rights to air seasons nine & ten.[154][155] On January 22, 2018, it was announced that Nine had acquired the rights to Season 1–8.[156]
Kaley Cuoco as Penny:[44] An aspiring actress from Omaha, Nebraska. Penny moves in across the hall from Sheldon and Leonard. She waits tables and occasionally tends the bar at the Cheesecake Factory. After giving up hope of becoming a successful actress, Penny becomes a pharmaceutical sales representative. Penny becomes friends with Bernadette and Amy, and they often hang out in each other's apartments. Penny and Leonard form a relationship and eventually marry.
The episode opens with a short montage of clips from the series' twelve seasons, then segues to Sheldon and Amy, who are up late waiting for a call from the Nobel Committee. Following a prank call from Kripke, they are told they've won the Nobel Prize in Physics for their super-asymmetry work. The attention from the media and the university bothers Sheldon. Amy is saddened by an unflattering picture of her in a news report, so Raj convinces her to get a makeover. She loves her new look but Sheldon demands she change it back. Leonard calls him out for being rude, but Sheldon flees when he sees Penny emerge from the newly repaired elevator. Sheldon and Penny go to the Cheesecake Factory and Penny tells Sheldon that change is the only constant thing in life. On a TV, they see Bernadette and Howard take credit as Sheldon and Amy's best friends. Raj and Leonard defend Amy, with Leonard accidentally breaking Sheldon's DNA molecule model in Apartment 4A. Penny convinces Sheldon to ride in the elevator.
Showrunner Steve Molaro, who took over from Bill Prady with the sixth season, credits some of the show's success to the sitcom's exposure in off-network syndication, particularly on TBS, while Michael Schneider of TV Guide attributes it to the timeslot move two seasons earlier. Chuck Lorre and CBS Entertainment president Nina Tassler also credit the success to the influence of Molaro, in particular the deepening exploration of the firmly established regular characters and their interpersonal relationships, such as the on-again, off-again relationship between Leonard and Penny.[103] Throughout much of the 2012–13 season, The Big Bang Theory placed first in all of syndication ratings, receiving formidable competition from only Judge Judy and Wheel of Fortune (first-run syndication programs). By the end of the 2012–13 television season, The Big Bang Theory had dethroned Judge Judy as the ratings leader in all of syndicated programming with 7.1, Judy descending to second place for that season with a 7.0.[104] The Big Bang Theory did not place first in syndication ratings for the 2013–14 television season, beaten out by Judge Judy.[105]
In March 2017, CBS renewed the series for two additional seasons, bringing its total to twelve, and running through the 2018–19 television season.[3] On August 22, 2018, CBS and Warner Bros. Television officially announced that the twelfth season would be the series' last. This stems from Jim Parsons' decision to leave the series at the end of the season if the show were to have been renewed for a thirteenth season.[1][4][5] The series concluded with an hour-long finale consisting of two back-to-back episodes on May 16, 2019.[6][7] A retrospective, hosted by Johnny Galecki and Kaley Cuoco, aired at 9:30 P.M. ET/PT, the night of the finale, following the season two finale of Young Sheldon.[8]
"The Plagiarism Schism" -- Pictured: Howard Wolowitz (Simon Helberg) and Bernadette (Melissa Rauch). Kripke (John Ross Bowie) has proof that Dr. Pemberton (Sean Astin) plagiarized his thesis in college, and Sheldon and Amy aren\'t sure if they should turn him in or not. Also, Wolowitz is happily surprised to learn that Bernadette wasn\'t the only waitress at the Cheesecake Factory who had a crush on him back in the day, on THE BIG BANG THEORY, Thursday, May 2 (8:00-8:31 PM, ET/PT) on the CBS Television Network. Photo: Michael Yarish/Warner Bros. Entertainment Inc. © 2019 WBEI. All rights reserved. (Photo: Michael Yarish, Warner Bros.)
Sheldon and Amy go on their honeymoon to New York City, starting with Legoland New York. Sheldon's insistence on scheduling their marital relations stresses Amy. He says he only does it to remind himself to be intimate with her. They compromise by letting him make a schedule without sharing it with her. Leonard and Penny discover Mr. Larry Fowler (Teller) in Sheldon and Amy's apartment hiding from his wife (Kathy Bates). Leonard notices parallels in his own marriage, which offends Penny. Leonard apologizes, and Penny convinces Mrs. Fowler to give her husband a break. When Mrs. Fowler wants to hang out with her regularly, Penny scares Larry out of the building. Raj instigates a Twitter feud with Neil deGrasse Tyson but is scared off when confronted over the phone. Neil then calls Bill Nye to scare him, too.
"It's different for everybody. It was time for me and I felt that. It's both simple and complicated. I don't have a diary that I could bring out and say, 'Here are the reasons as far as quote-unquote future plans in a concrete way or (that I had) a problem with coming here.' None of those things were true," he says. "I felt it was the right moment for me. But, it only helps so much to go through the end of something like this feeling you've made the right choice. It's still exceedingly emotional." 
Penny, who admits to missing Leonard in "The Roommate Transmogrification", accepts his request to renew their relationship in "The Beta Test Initiation". After Penny suggests having sex in "The Launch Acceleration", Leonard breaks the mood by proposing to her. Penny says "no" but does not break up with him. She stops a proposal a second time in "The Tangible Affection Proof". In the sixth-season episode, "The 43 Peculiarity", Penny finally tells Leonard that she loves him. Although they both feel jealousy when the other receives significant attention from the opposite sex, Penny is secure enough in their relationship to send him off on an exciting four-month expedition without worrying in "The Bon Voyage Reaction". After Leonard returns, their relationship blossoms over the seventh season. In the penultimate episode "The Gorilla Dissolution", Penny admits that they should marry and when Leonard realizes that she is serious, he proposes with a ring that he had been saving for years. Leonard and Penny decide to elope to Las Vegas in the season 8 finale, but beforehand, wanting no secrets, Leonard admits to kissing another woman, Mandy Chow (Melissa Tang) while on an expedition on the North Sea. Despite this, Leonard and Penny finally elope in the season 9 premiere.
With Leonard, Howard, Raj, and Amy accomplishing so much on their respective projects, Sheldon is forced to admit he has nothing important upon which to work. He makes Amy leave the apartment for a few days so he can focus, but cannot come up with any ideas and calls his mother as a distraction. Leonard and Amy have fun recreating experiments from when they were growing up, boring Penny, so she eats with Sheldon as he mulls over his scientific studies. Penny helps him realize that his study of dark matter is his rebound science from string theory, which Sheldon admits he never truly disregarded, but explaining string theory to her inspires Sheldon, helping him discover a potential breakthrough in the field. Meanwhile Howard is too busy with his family to be in the band with Raj, so Raj brings in Bert. But, when Howard annoys Bernadette by writing an astronaut-themed musical while she is on bed-rest, she makes him rejoin the band. The three are poorly received at a Bar mitzvah after singing Bert's original song about the boulder from Indiana Jones .

The scene is all business – at least as much as you can expect from a bunch of cut-ups making a sitcom – and no one seems distracted by two significant events: The episode will mark the show’s 276th, moving it past “Cheers” to set a record for a sitcom filmed in front of a studio audience, and only three more remain to be shot for "Big Bang," co-created by Chuck Lorre and Bill Prady. 
I am one of these people. And I have identified so much with Sheldon throughout the series, I do not struggle as hard as he did/do, but I have a good understanding of how it feels. And even worse, the realization of how it affects the ones closest to me. Ofc, I have come a far away with this. Intense therapy etc. But it is still there, like a haunting memory.
Raj meets with the woman his father set up for him, Anu. Her commanding personality and practical approach to marriage startle Raj but he agrees to go ahead with it. Howard criticizes him but apologizes; he just never expected Raj to give up on romance. Raj admits this to Anu so she proposes to him, and he says yes. Raj also sends out a relationship questionnaire to Leonard and Penny, which soon reveals that Penny does not think she ever wants kids, upsetting Leonard, who would like to have kids someday, and their friends selfishly badger them on the issue. After telling her father Wyatt who is also upset, Leonard tells Penny that he'll be okay with it, as he never thought he'd have her in his life. To get his mind off of it, Penny rents Leonard a Batmobile to drive in and have fun with for the day. Meanwhile, Stuart starts bringing home Denise at night, which is very uncomfortable for Howard and Bernadette. When they also try to have time to themselves, they wake up their kids.
I had never heard of Jim Parsons until I watched BBT but, his performance as Sheldon Cooper should be recognized as one of the greatest in TV history and the individual responsible for casting him should be considered a genius. Jim was born to play Sheldon. No other actor could’ve owned this character the way he did. I hope he continues to share his talent with audiences in other ways!
In the episode "The Launch Acceleration", Amy tries to use her "neurobiology bag of tricks" to increase the attraction between herself and Sheldon. In the final fifth-season episode "The Countdown Reflection", Sheldon takes Amy's hand as Howard is launched into space. In the sixth season first episode "The Date Night Variable", after a dinner in which Sheldon fails to live up to this expectation, Amy gives Sheldon an ultimatum that their relationship is over unless he tells her something from his heart. Amy accepts Sheldon's romantic speech even after learning that it is a line from the first Spider-Man movie. In "The Cooper/Kripke Inversion" Sheldon states that he has been working on his discomfort about physical contact and admits that "it's a possibility" that he could one day have sex with Amy. Amy is revealed to have similar feelings in "The Love Spell Potential". Sheldon explains that he never thought about intimacy with anyone before Amy.[82]
The Canadian alternative rock band Barenaked Ladies wrote and recorded the show's theme song, which describes the history and formation of the universe and the Earth. Co-lead singer Ed Robertson was asked by Lorre and Prady to write a theme song for the show after the producers attended one of the band's concerts in Los Angeles. By coincidence, Robertson had recently read Simon Singh's book Big Bang,[25][26] and at the concert improvised a freestyle rap about the origins of the universe.[citation needed] Lorre and Prady phoned him shortly thereafter and asked him to write the theme song. Having been asked to write songs for other films and shows, but ending up being rejected because producers favored songs by other artists, Robertson agreed to write the theme only after learning that Lorre and Prady had not asked anyone else.[citation needed]
The first and second seasons were only available on DVD at their time of release in 2008[197] and 2009.[198] Starting with the release of the third season in 2010[199] and continuing every year with every new season, a Blu-ray disc set has also been released in conjunction with the DVD. In 2012, Warner Bros. released the first two seasons on Blu-ray,[200] marking the first time that all episodes were available on the Blu-ray disc format.
While Johnny Galecki is putting down the comic books for good as he says goodbye to experimental physicist Leonard Hofstadter, he's poised to return to another iconic role one more with the expanded season two order of Roseanne spinoff The Conners coming to ABC this fall. Galecki reprised the role of David Healy, ex-husband to Sara Gilbert's Darlene, for a handful of episodes in the show's first season and the door was definitely left open for more. Despite Galecki telling TV Line in February that he wouldn't consider jumping in full-time—"I think I need a little bit of space from being a series regular again," he said—he's hoping to "visit as much as possible." And Gilbert, who serves as EP on the series, remains hopeful as well. "I know he loves doing the show. I love having him. We have a magical time together," she told the outlet in January. "I would anticipate that he would do some [episodes] but I don't want to speak for him."
However, no legal action was required to end production of the other show: as soon as it became known that the show was unlicensed, the actors quit and the producers canceled it.[209] Dmitriy Tankovich (who plays Leonard's counterpart, "Seva") said in an interview, "I'm upset. At first, the actors were told all legal issues were resolved. We didn't know it wasn't the case, so when the creators of The Big Bang Theory started talking about the show, I was embarrassed. I can't understand why our people first do, and then think. I consider this to be the rock bottom of my career. And I don't want to take part in a stolen show".[210]
It’s no secret that the cast of The Big Bang Theory gets paid out for every episode. But, who is the richest Big Bang Theory cast member? As it turns out, the show’s lead, Jim Parsons is the highest earning actor on the hit television series. The actor, who plays Sheldon Cooper, is worth $70 million and brings in $900,000 per episode on The Big Bang Theory (he and some of his castmates made $1 million per episode, but took a $100,000 pay cut so some of the other supporting roles could get a raise).

I love the show and cant believe it is done. I feel that that final episode left me wanting more. It did answer alot of questions that where asked about the show but I feel that it also made more come up that wont be answered.i hope that there will be a spin off to the series with the crew that wants to just because jim parson wants to move on to other things i hope it doesnt stop the rest of them to stop.

Two nerdy physicists share an apartment and an unlikely friendship with their beautiful neighbor with whom one of them is infatuated. Like the universe after the big bang, the show's popularity expanded, thanks to breakout star Jim Parsons, along with the chemistry among the friends and the developing romance between Leonard and Penny. The addition of Melissa Rauch and Mayim Bialik in later seasons also enhanced the stories and relationships of the leads.

He's since become attached to a handful of Netflix projects, appearing in their recent Ted Bundy film Extremely Wicked, Shockingly Evil and Vile, executive producing mentee Ryan O'Connell's autobiographical comedy series Special, and signing on to reprise his role in their movie version of Ryan Murphy's Broadway production of The Boys in the Band, due on the streaming service in 2020.
Howard dresses as Sheldon for Halloween at work, hurting Sheldon's feelings. When Howard does not apologize, Amy and Sheldon dress as Bernadette and Howard at Penny and Leonard's party, angering Bernadette. Sheldon and Bernadette later bond over their painful childhood memories. Leonard is upset that Penny does not seem to remember that their first kiss was on Halloween. Penny later admits she does remember, but does not like to think of their first kiss as an unromantic drunken hookup. She likes to imagine their first kiss was one they shared on Leonard's birthday, which pleases him.

President Siebert charges Leonard with distributing some extra university funds in the form of a grant. Everyone begins sucking up to Leonard. Penny is impressed by Leonard's decisiveness but unimpressed when he cannot decide between Raj, Kripke and Dr. Lee (Maribeth Monroe), an ornithologist who works with crows. Leonard, realizing that people will be angry with him no matter who he gives the funds to, eventually awards the money to himself; many crows swarm his car afterwards. Meanwhile, a stressed out Bernadette starts hiding in Halley's playhouse after work so she can have time to herself. She is eventually joined by Penny and Amy. Howard reveals to Raj that he actually knows that Bernadette has been hiding out, but is keeping quiet about it so she can have her privacy and so he can use it to his advantage.
The Big Bang Theory premiered in the United States on September 24, 2007 on CBS. The series debuted in Canada on CTV in September 2007.[152] On February 14, 2008, the series debuted in the United Kingdom on channels E4 and Channel 4.[153] In Australia the first seven seasons of the series began airing on the Seven Network and 7mate from October 2015 and also gained the rights to season 8 in 2016, though the Nine Network has rights to air seasons nine & ten.[154][155] On January 22, 2018, it was announced that Nine had acquired the rights to Season 1–8.[156]

However, no legal action was required to end production of the other show: as soon as it became known that the show was unlicensed, the actors quit and the producers canceled it.[209] Dmitriy Tankovich (who plays Leonard's counterpart, "Seva") said in an interview, "I'm upset. At first, the actors were told all legal issues were resolved. We didn't know it wasn't the case, so when the creators of The Big Bang Theory started talking about the show, I was embarrassed. I can't understand why our people first do, and then think. I consider this to be the rock bottom of my career. And I don't want to take part in a stolen show".[210]

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