In the apartment building where Sheldon, Leonard and Penny (and later Amy) live, the elevator has been out of order throughout most of the series, forcing characters to have to use the stairs. Stairway conversations between characters occur in almost every episode, often serving as a transition between longer scenes. The Season 3 episode, "The Staircase Implementation" reveals that the elevator was broken when Leonard was experimenting with rocket fuel. In the penultimate episode of the series, the elevator is returned to an operational state, causing Sheldon some angst.
However, no legal action was required to end production of the other show: as soon as it became known that the show was unlicensed, the actors quit and the producers canceled it. Dmitriy Tankovich (who plays Leonard's counterpart, "Seva") said in an interview, "I'm upset. At first, the actors were told all legal issues were resolved. We didn't know it wasn't the case, so when the creators of The Big Bang Theory started talking about the show, I was embarrassed. I can't understand why our people first do, and then think. I consider this to be the rock bottom of my career. And I don't want to take part in a stolen show".
Leonard's mother Beverly visits, and he is thrilled when she takes an interest in his work. However, when he learns that she is doing research on him for a new parenting book, he is furious. He prepares to tell her how she let him down over the years, but instead chooses to accept and forgive her, and forgive himself for holding onto that resentment for so long. Beverley is touched that he forgave her and they share a genuine hug. Meanwhile, Anu gets a job offer in London. Raj prepares to fly out and propose to her, ready to follow her if she accepts. Howard stops Raj at the airport, saying there is a better match out there for him, convincing Raj to return home. Stuart and Denise are bothered by her creepy roommate Mitch, while Bernadette and Howard are tired of Denise constantly staying overnight with Stuart at their house. Stuart says he is ready to move in with Denise, and they say they love each other while convincing Mitch to move out.
Two physicists from Chicago, Dr. Campbell and Dr. Pemberton, accidentally prove Sheldon and Amy's super-asymmetry theory. This puts them on track for a Nobel Prize, but Leonard points out they tend to go to the experimental scientists who prove a concept instead of theorists like Sheldon who come up with it. Meeting with them, they tell Sheldon they are willing to share the Prize but only three names can be on the submission, and they want to cut Amy out. Amy does not want to prevent Sheldon's lifelong dream, but he goes to President Seibert who agrees to fight for Amy on their behalf. Meanwhile, Bernadette's drug has been approved and she wants to promote Penny to lead the marketing team. Penny resists, knowing Bernadette's attitude at work and doubting her own inexperience to take the responsibility, but Bernadette uses reverse-psychology to get Penny to take the job. Penny mirrors Bernadette's commanding style to get the other employees in line, impressing Bernadette.
On March 13, 2017, CBS ordered the spin-off Young Sheldon series. Jon Favreau directed and executive produced the pilot. Created by Lorre and Molaro, the series follows 9-year-old Sheldon Cooper as he attends high school in East Texas. Alongside Armitage as 9-year-old Sheldon Cooper and Perry as Mary Cooper, Lance Barber stars as George Cooper, Sheldon's father; Raegan Revord stars as Missy Cooper, Sheldon's twin sister; and Montana Jordan as George Cooper Jr., Sheldon's older brother. Jim Parsons reprises his role as adult Sheldon Cooper, as narrator for the series. Parsons, Lorre, Molaro and Todd Spiewak will also serve as executive producers on the series, for Chuck Lorre Productions, Inc. in association with Warner Bros. Television. The show's pilot episode premiered on September 25, 2017. Subsequent weekly episodes began airing on November 2, 2017 following the broadcast of the 237th episode of The Big Bang Theory.
Science has also interfered with the characters' romantic lives. Leslie breaks up with Leonard when he sides with Sheldon in his support for string theory rather than loop quantum gravity. When Leonard joins Sheldon, Raj, and Howard on a three-month Arctic research trip, it separates Leonard and Penny at a time when their relationship is budding. When Bernadette takes an interest in Leonard's work, it makes both Penny and Howard envious and results in Howard confronting Leonard, and Penny asking Sheldon to teach her physics. Sheldon and Amy also briefly end their relationship after an argument over which of their fields is superior.
The Big Bang Theory signs off for good on Thursday, May 16, meaning that there's only one last bazinga left in the pipeline before we're forced to say farewell to Sheldon, Leonard, Penny, and the gang after 12 laugh-filled seasons. And while there's still a few questions left to be answered by the big one-hour series finale—Will the elevator ever be fixed? And will we ever learn Penny's maiden name?—there's a bigger one looming for when the credits roll and it's all over.
In the show, the song "Soft Kitty" was described by Sheldon as a song sung by his mother when he was ill. Its repeated use in the series popularized the song. A scene depicting the origin of the song in Sheldon's childhood is depicted in an episode of Young Sheldon, which aired on February 1, 2018. It shows Sheldon's mother Mary singing the song to her son, who is suffering with the flu.
When Mayim Bialik first learned she had to say goodbye to neurobiologist Amy Farrah Fowler, she opened up about the show ending in a blog post, asking, "And now I start to figure out what next. Where will life take me? Where will this career go? What do I want?" Up next she has a voice role in The Inspector Chronicles, a quasi-parody of Doctor Who making the leap from short to feature film. She'll reprise her role as the voice of the Inspector's time machine, known as B.O.O.T.H. Aside from that, she doesn't have any major projects lined up, aside from preparing to not see her close-knit cast the way she'd grown accustomed to. "We'll have to see what our lives look like," she told Us Weekly in early May about the chance they'll remain close. "I mean, we're all going to be on different schedules now; it's very different."