Star Trek in particular is frequently referenced and Sheldon identifies strongly with the character of Spock, so much so that when he is given a used napkin signed by Leonard Nimoy as a Christmas gift from Penny he is overwhelmed with excitement and gratitude ("I possess the DNA of Leonard Nimoy?!").[73] Star Trek: The Original Series cast member George Takei has made a cameo, and Leonard Nimoy made a cameo as the voice of Sheldon's vintage Mr. Spock action figure (both cameos were in dream sequences). Star Trek: The Next Generation cast members Brent Spiner and LeVar Burton have had cameos as themselves,[74][75] while Wil Wheaton has a recurring role as a fictionalized version of himself. Leonard and Sheldon have had conversations in the Klingon language.
Melissa Rauch as Bernadette Rostenkowski-Wolowitz (recurring season 3, starring seasons 4–12):[51] A young woman who initially is a co-worker at The Cheesecake Factory with Penny to pay her way through graduate school, where she is studying microbiology. Bernadette is introduced to Howard by Penny; at first, they do not get along, apparently having nothing in common. They date and later get engaged and married. Although generally a sweet and good-natured person, Bernadette has a short fuse and can be vindictive and lash out when provoked.
By season seven, Galecki, Parsons, and Cuoco were also receiving 0.25% of the series' back-end money. Before production began on the eighth season, the three plus Helberg and Nayyar, looked to renegotiate new contracts, with Galecki, Parsons, and Cuoco seeking around $1 million per episode, as well as more back-end money.[36] Contracts were signed in the beginning of August 2014, giving the three principal actors an estimated $1 million per episode for three years, with the possibility to extend for a fourth year. The deals also include larger pieces of the show, signing bonuses, production deals, and advances towards the back-end.[37] Helberg and Nayyar were also able to renegotiate their contracts, giving them a per-episode pay in the "mid-six-figure range", up from around $100,000 per episode they each received in years prior. The duo, who were looking to have salary parity with Parsons, Galecki, and Cuoco, signed their contracts after the studio and producers threatened to write the characters out of the series if a deal could not be reached before the start of production on season eight.[38] By season 10, Helberg and Nayyar reached the $1 million per episode parity with Parsons, Galecki, and Cuoco, due to a clause in their deals signed in 2014.[39]
The episode opens with a short montage of clips from the series' twelve seasons, then segues to Sheldon and Amy, who are up late waiting for a call from the Nobel Committee. Following a prank call from Kripke, they are told they've won the Nobel Prize in Physics for their super-asymmetry work. The attention from the media and the university bothers Sheldon. Amy is saddened by an unflattering picture of her in a news report, so Raj convinces her to get a makeover. She loves her new look but Sheldon demands she change it back. Leonard calls him out for being rude, but Sheldon flees when he sees Penny emerge from the newly repaired elevator. Sheldon and Penny go to the Cheesecake Factory and Penny tells Sheldon that change is the only constant thing in life. On a TV, they see Bernadette and Howard take credit as Sheldon and Amy's best friends. Raj and Leonard defend Amy, with Leonard accidentally breaking Sheldon's DNA molecule model in Apartment 4A. Penny convinces Sheldon to ride in the elevator.
Howard dresses as Sheldon for Halloween at work, hurting Sheldon's feelings. When Howard does not apologize, Amy and Sheldon dress as Bernadette and Howard at Penny and Leonard's party, angering Bernadette. Sheldon and Bernadette later bond over their painful childhood memories. Leonard is upset that Penny does not seem to remember that their first kiss was on Halloween. Penny later admits she does remember, but does not like to think of their first kiss as an unromantic drunken hookup. She likes to imagine their first kiss was one they shared on Leonard's birthday, which pleases him.
In scenes set at Howard's home, he interacts with his rarely-seen mother (voiced by Carol Ann Susi until her death) by shouting from room to room in the house. She similarly interacts with other characters in this manner.[85] She reflects the Jewish mother stereotype in some ways, such as being overly controlling of Howard's adult life and sometimes trying to make him feel guilty about causing her trouble. She is dependent on Howard, as she requires him to help her with her wig and makeup in the morning. Howard, in turn, is attached to his mother to the point where she still cuts his meat for him, takes him to the dentist, does his laundry and "grounds" him when he returns home after briefly moving out.[86] Until Howard's marriage to Bernadette in the fifth-season finale, Howard's former living situation led Leonard's psychiatrist mother to speculate that he may suffer from some type of pathology,[87] and Sheldon to refer to their relationship as Oedipal.[88] In season 8, Howard's mother dies in her sleep while in Florida, which devastates Howard and Stuart, who briefly lived with Mrs. Wolowitz.

Raj meets with the woman his father set up for him, Anu. Her commanding personality and practical approach to marriage startle Raj but he agrees to go ahead with it. Howard criticizes him but apologizes; he just never expected Raj to give up on romance. Raj admits this to Anu so she proposes to him, and he says yes. Raj also sends out a relationship questionnaire to Leonard and Penny, which soon reveals that Penny does not think she ever wants kids, upsetting Leonard, who would like to have kids someday, and their friends selfishly badger them on the issue. After telling her father Wyatt who is also upset, Leonard tells Penny that he'll be okay with it, as he never thought he'd have her in his life. To get his mind off of it, Penny rents Leonard a Batmobile to drive in and have fun with for the day. Meanwhile, Stuart starts bringing home Denise at night, which is very uncomfortable for Howard and Bernadette. When they also try to have time to themselves, they wake up their kids.

Bernadette's due date arrives but she still hasn't given birth. As Amy and Howard work together at the college, the rest of the friends try various ways to initiate her labor, though Sheldon wants to play a complicated board game instead. Amy shocks Howard by saying Bernadette has already decided to name the baby after her father, Michael. He doesn't agree and everyone makes suggestions as to what to name the baby. Bernadette goes into labor and gives birth to a son named Neil, after Neil Armstrong, Neil Gaiman, and Neil Diamond, with Michael as the middle name. At the last minute, Howard relents to name him Michael as Bernadette got six stitches.
Raj meets with the woman his father set up for him, Anu. Her commanding personality and practical approach to marriage startle Raj but he agrees to go ahead with it. Howard criticizes him but apologizes; he just never expected Raj to give up on romance. Raj admits this to Anu so she proposes to him, and he says yes. Raj also sends out a relationship questionnaire to Leonard and Penny, which soon reveals that Penny does not think she ever wants kids, upsetting Leonard, who would like to have kids someday, and their friends selfishly badger them on the issue. After telling her father Wyatt who is also upset, Leonard tells Penny that he'll be okay with it, as he never thought he'd have her in his life. To get his mind off of it, Penny rents Leonard a Batmobile to drive in and have fun with for the day. Meanwhile, Stuart starts bringing home Denise at night, which is very uncomfortable for Howard and Bernadette. When they also try to have time to themselves, they wake up their kids. 

When Mayim Bialik first learned she had to say goodbye to neurobiologist Amy Farrah Fowler, she opened up about the show ending in a blog post, asking, "And now I start to figure out what next. Where will life take me? Where will this career go? What do I want?" Up next she has a voice role in The Inspector Chronicles, a quasi-parody of Doctor Who making the leap from short to feature film. She'll reprise her role as the voice of the Inspector's time machine, known as B.O.O.T.H. Aside from that, she doesn't have any major projects lined up, aside from preparing to not see her close-knit cast the way she'd grown accustomed to. "We'll have to see what our lives look like," she told Us Weekly in early May about the chance they'll remain close. "I mean, we're all going to be on different schedules now; it's very different."
Initial reception for the series was mixed. The review aggregation website Rotten Tomatoes reported a 52% approval rating for the first season based on reviews from 23 critics, with an average rating of 5.18/10. The website's critical consensus reads, "The Big Bang Theory brings a new class of character to mainstream television, but much of the comedy feels formulaic and stiff."[91] On Metacritic, the season holds a score of 57 out of 100, based on reviews from 23 critics, indicating "mixed or average reviews".[92] Later seasons received more acclaim and in 2013, TV Guide ranked the series #52 on its list of the 60 Best Series of All Time.[93]
In March 2017, CBS renewed the series for two additional seasons, bringing its total to twelve, and running through the 2018–19 television season.[3] On August 22, 2018, CBS and Warner Bros. Television officially announced that the twelfth season would be the series' last. This stems from Jim Parsons' decision to leave the series at the end of the season if the show were to have been renewed for a thirteenth season.[1][4][5] The series concluded with an hour-long finale consisting of two back-to-back episodes on May 16, 2019.[6][7] A retrospective, hosted by Johnny Galecki and Kaley Cuoco, aired at 9:30 P.M. ET/PT, the night of the finale, following the season two finale of Young Sheldon.[8]
On March 16, 2014, a Lego Ideas project[206] portraying the living room scene in Lego style with the main cast as mini-figures reached 10,000 supporters on the platform, which qualified it to be considered as an official set by the Lego Ideas review board. On November 7, 2014, Lego Ideas approved the design and began refining it. The set was released in August 2015, with an exclusive pre-sale taking place at the San Diego Comic-Con International.[citation needed]
Sheldon is still despondent over the disproving of his and Amy's theory on asymmetry. Leonard brings out a VHS tape of a pep talk that Sheldon recorded as a boy, but it turns out that his father had recorded a long-ago football game over it. Sheldon, however, is buoyed by a halftime pep talk his father gave the team, realizing he and his father had more in common than he previously thought. This causes Amy to view asymmetry and symmetry in another manner and they decide their theory may not be dead after all. Bernadette finds an old tape of Howard preparing to audition for The Magic Castle. She insists he fulfill his dream and audition with her as a coach, drawing on her beauty pageant experience. Howard eventually decides to audition his own way, and promptly botches his chances by accidentally destroying a judge's Rolex.
After learning Sheldon went behind their backs to work with the military again, Leonard and Howard say Sheldon is like Thomas Edison, taking credit for others' ideas, while they are more like Nikola Tesla. Leonard and Howard bring in Barry Kripke to help create a better idea than Sheldon's, but Kripke goes to the military himself, cutting all three of them out. Meanwhile, Bernadette fears Ruchi is trying to steal her projects at work while she is on maternity leave and enlists Raj to spy on her. Though he finds proof that Ruchi may be stealing from Bernadette, Raj tries to defend Ruchi like a boyfriend would, pointing out Bernadette's hypocrisy as she would most likely have stolen from other people's projects as well. Ruchi is not happy about this and promptly dumps Raj. 

I read through the article and all the comments (which makes me miss TBBT even more and it hasn’t been off the air a week yet) and noticed that 3 of my favs aren’t mentioned. (1) episode where a bully (Todd Sornecki) steals Sheldon’s online trophies and Penny kicks him in the nuts for Sheldon; (2) the episode where they reveals each others secrets (Leonard slept with Priya; Raj used Sheldon’s tooth brush; Howard told Raj foreigner give gifts to Americans for certain holidays and Sheldon put moths in Leonards food “for science”; (3) the episode where Amy and Sheldon go to the aquarium “as friends”, when Sheldon tells Amy “I can handle a lot of things Amy but getting over you isn’t one of them, I think we should just be friends” it breaks my heart everytime; (4) the episode where Priya buys Leonard glass and he walks into the cafeteria and causes mass chaos, that’s a classic; (5) the episode where Priya ruins the roommate agreement between Sheldon and Leonard, when Leonard buys Sheldon Greek food it’s hilarious. Sheldon gets back at Leonard & Priya by threatening to send an email to Priya’s parents telling that “she’s in a relationship with the whiter than marsmellow fluff Leonard Hofstedter”. Ok just one more, when they all take a road trip to speak at the science convention and Bernadette runs into her former professor/lover played by Rick Foxx and Sheldon banished Penny to the “love car” and Bernie and Howard sing Sonny & Cher “I got you Babe” is funnier than hell. I still crack up when I see Raj look down at Howard’s junk to measure Howard’s junk against Rick Foxx’s, I can’t believe the sensors let that through. 
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