Producers, writers and others, including recurring guest star Wil Wheaton, joined the festivities on set and — hardly a spoiler alert — more laughing, crying and hugging ensued. Lorre embraced a happy Parsons, then moved on to each cast member as if it were a reception line. Galecki shared long, emotional hugs with his colleagues. After trying to keep their emotions under control for so long, it was finally time to just let go.
Kaley Cuoco's life after The Big Bang Theory is going to be animated. Cuoco has signed on to voice and executive produce DC Universe's new Harley Quinn series. She'll play the titular character in the new streaming series targeted toward mature audiences. In 2017, she got the rights to The Flight Attendant, a miniseries based on the book of the same name, which she was poised to star in. The Flight Attendant follows Cassandra Bowden, a flight attendant, who wakes up, hungover, in her hotel room with a dead body next to her. She goes about her day and heads back to New York. is she the killer? That's what she wonders. "This is the first time I have a project that I'm kind of nurturing from the beginning, so it's been a really interesting experience," she told PopSugar in March. "It's got a lot of aspects. It's very sexy. It's a really well-written book, which is why I wanted to option it. I'm ready to bring the character to life."
As Sheldon and Amy start to plan their wedding, they use decision theory to limit the stress of choosing between their competing visions for the big day. After they begin to question each other’s decisions and make deliberately provocative choices, they decide to have a simple wedding at City Hall. As they wait their turn, Sheldon changes his mind and decides he wants a first dance with Amy at a real wedding.
In November 2016, it was reported that CBS was in negotiations to create a spin-off of The Big Bang Theory centered on Sheldon as a young boy. The prequel series, described as "a Malcolm in the Middle-esque single-camera family comedy" would be executive-produced by Lorre and Molaro, with Prady expected to be involved in some capacity, and intended to air in the 2017–18 season alongside The Big Bang Theory.[211][212] The initial idea for the series came from Parsons, who passed it along to The Big Bang Theory producers.[213] In early March 2017, Iain Armitage was cast as the younger Sheldon, as well as Zoe Perry as his mother, Mary Cooper. Perry is the real-life daughter of Laurie Metcalf, who portrays Mary Cooper on The Big Bang Theory.[213]

Howard dresses as Sheldon for Halloween at work, hurting Sheldon's feelings. When Howard does not apologize, Amy and Sheldon dress as Bernadette and Howard at Penny and Leonard's party, angering Bernadette. Sheldon and Bernadette later bond over their painful childhood memories. Leonard is upset that Penny does not seem to remember that their first kiss was on Halloween. Penny later admits she does remember, but does not like to think of their first kiss as an unromantic drunken hookup. She likes to imagine their first kiss was one they shared on Leonard's birthday, which pleases him.
The episode opens with a short montage of clips from the series' twelve seasons, then segues to Sheldon and Amy, who are up late waiting for a call from the Nobel Committee. Following a prank call from Kripke, they are told they've won the Nobel Prize in Physics for their super-asymmetry work. The attention from the media and the university bothers Sheldon. Amy is saddened by an unflattering picture of her in a news report, so Raj convinces her to get a makeover. She loves her new look but Sheldon demands she change it back. Leonard calls him out for being rude, but Sheldon flees when he sees Penny emerge from the newly repaired elevator. Sheldon and Penny go to the Cheesecake Factory and Penny tells Sheldon that change is the only constant thing in life. On a TV, they see Bernadette and Howard take credit as Sheldon and Amy's best friends. Raj and Leonard defend Amy, with Leonard accidentally breaking Sheldon's DNA molecule model in Apartment 4A. Penny convinces Sheldon to ride in the elevator.

Kunal Nayyar has the flick Think Like a Dog in post-production and the upcoming Trolls World Tour in pre-production. Nayyar provides the voice of Guy Diamond in the movie series. Aside from that, however, the former Raj Koothrappali is looking forward to some much needed family time. "I'm going to go to India, spend more time with my parents," he told Parade in late April. "I left my country when I was 18, so it's important for me to go home and spend time with mom and dad, so that's the main focus right now.
President Siebert charges Leonard with distributing some extra university funds in the form of a grant. Everyone begins sucking up to Leonard. Penny is impressed by Leonard's decisiveness but unimpressed when he cannot decide between Raj, Kripke and Dr. Lee (Maribeth Monroe), an ornithologist who works with crows. Leonard, realizing that people will be angry with him no matter who he gives the funds to, eventually awards the money to himself; many crows swarm his car afterwards. Meanwhile, a stressed out Bernadette starts hiding in Halley's playhouse after work so she can have time to herself. She is eventually joined by Penny and Amy. Howard reveals to Raj that he actually knows that Bernadette has been hiding out, but is keeping quiet about it so she can have her privacy and so he can use it to his advantage.
Campbell and Pemberton start a publicity tour for their Nobel campaign, including appearing on The Ellen DeGeneres Show. Caltech reaches out to previous winners, including George Smoot, Kip Thorne and Frances H. Arnold, only to find that Sheldon has offended most of them in the past. Leonard and Penny convince them to show up to the reception, only for Pemberton and Campbell to crash the party. Leonard holds Sheldon back, only for Amy to verbally snap at them. Meanwhile, with Halley scared of the dark, Stuart and Bernadette turn Howard's story from his time in outer space into the children's book: The Frightened Little Astronaut. Howard is embarrassed until Bernadette talks him into helping children and Stuart's art career by letting it be published.

After Sheldon reminds the guys about the time they mined Bitcoin without him, the guys go on a quest to find their suddenly valuable missing cryptocurrency. They realize the currency is on a laptop which Leonard gave to Penny when they dating, which she then gave to her ex-boyfriend Zack. After Leonard and Penny go to Zack's apartment, he shows them a seven-year-old video that Penny recorded on the laptop soon after she broke up with Leonard. Leonard is touched by the video which shows a drunk Penny lamenting the break-up of her relationship with him.
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