Professor Proton, Sheldon's favorite childhood show, is being rebooted. After unsuccessfully auditioning for the part, he goes to Wil Wheaton for acting tips for his second audition. However, Sheldon is later dismayed when Wil is offered the role instead. Talking it over with Arthur in his dreams, he is still upset to see his idol replaced and considers Wil an enemy again. Meanwhile, Howard gets a vasectomy while Bernadette is on bed rest. Penny offers to take care of Halley for them, but they insult her by expecting her to be irresponsible. Halley ends up saying her first word by calling Penny "Mama."
When Penny tells Leonard he needs to be more assertive in making decisions for himself, he starts standing up to Sheldon over small things. His confidence makes him want to demand the university support his idea for a plasma physics project. He threatens to quit if the university refuses, alarming both Sheldon and Penny, who consider this to be a risky career move. Sheldon is conflicted on whether or not he is being selfish over Leonard's decision, but Amy suggests that the fact that he is worried over Leonard's motivation proves that he does care about him, which he acknowledges. President Seibert refuses the project, but in order not to lose Leonard, gives him co-leadership over a photon entanglement project, leaving Leonard proud of himself and Penny impressed. Meanwhile, Raj shows Anu his lab, and suggests one possible answer for something he's seen in space might be alien life. When someone mentions this at his observatory presentation, the scientific community starts mocking him as a conspiracy theorist. Raj points out scientists should consider all possibilities when seeking the truth, though this causes people to think he believes in the Loch Ness Monster.
In the third-season finale, Raj and Howard sign Sheldon up for online dating to find a woman compatible with Sheldon and discover neurobiologist Amy Farrah Fowler. Like him, she has a history of social ineptitude and participates in online dating only to fulfill an agreement with her mother. This spawns a storyline in which Sheldon and Amy communicate daily while insisting to Leonard and Penny that they are not romantically involved. In "The Agreement Dissection", Sheldon and Amy talk in her apartment after a night of dancing and she kisses him on the lips. Instead of getting annoyed, Sheldon says "fascinating" and later asks Amy to be his girlfriend in "The Flaming Spittoon Acquisition". The same night he draws up "The Relationship Agreement" to verify the ground rules of him as her boyfriend and vice versa (similar to his "Roommate Agreement" with Leonard). Amy agrees but later regrets not having had a lawyer read through it.
Simon Helberg as Howard Wolowitz:[45] An aerospace engineer who got his Masters at MIT. Howard is Jewish and lived with his mother, Debbie (Carol Ann Susi). Unlike Sheldon, Leonard, Raj, Bernadette and Amy, Howard does not hold a doctorate. He goes into space, training as an astronaut and serving as a payload specialist. Howard initially fancies himself as a womanizer, but he later starts dating Bernadette, and they get engaged and married. Howard also has a tendency to waste money on toys and argues with Bernadette because of his oddly low income as an engineer and her high income as a pharmaceutical biochemist.
Science has also interfered with the characters' romantic lives. Leslie breaks up with Leonard when he sides with Sheldon in his support for string theory rather than loop quantum gravity.[70] When Leonard joins Sheldon, Raj, and Howard on a three-month Arctic research trip, it separates Leonard and Penny at a time when their relationship is budding. When Bernadette takes an interest in Leonard's work, it makes both Penny and Howard envious and results in Howard confronting Leonard, and Penny asking Sheldon to teach her physics.[71] Sheldon and Amy also briefly end their relationship after an argument over which of their fields is superior.[72]
Filming proceeds smoothly – makeup artists do touch-ups, a prop master replenishes the pickle supply – with humor and camaraderie between takes. When a reshoot is needed because Simon Helberg, who plays Howard, held his napkin in the wrong hand, Kaley Cuoco, who plays Penny, lifts her food box high and mockingly asks, “Does it go over my head? I don’t remember.”

However, no legal action was required to end production of the other show: as soon as it became known that the show was unlicensed, the actors quit and the producers canceled it.[209] Dmitriy Tankovich (who plays Leonard's counterpart, "Seva") said in an interview, "I'm upset. At first, the actors were told all legal issues were resolved. We didn't know it wasn't the case, so when the creators of The Big Bang Theory started talking about the show, I was embarrassed. I can't understand why our people first do, and then think. I consider this to be the rock bottom of my career. And I don't want to take part in a stolen show".[210]
Sheldon and Amy struggle to choose a best man and maid of honor from their friends. They secretly decide to test and score them, allowing everyone to have an equal shot at either role. Once the gang finds out, none of them apart from Bernadette and Stuart want to be in the wedding. Sheldon settles for Stuart as best man but, once Leonard tells Sheldon that, as the groom, the decision is his alone, he picks Leonard. Amy is set to call Bernadette but, once Penny realizes Amy is her best friend, she immediately pitches herself for the position and Amy enthusiastically chooses her. Amy later makes Penny tell Bernadette the bad news.
Kunal Nayyar as Rajesh Koothrappali:[46] A particle astrophysicist originally from New Delhi, India. Raj is initially unable to talk to women unless he drinks alcohol. Raj also has very feminine tastes and often takes on a stereotypical female role in his friendship with Howard as well as in the group of four men. Raj later dates Lucy (Kate Micucci), who also suffers from social anxiety, but it eventually ends; he later speaks to Penny without alcohol and thus overcomes his selective mutism. He begins dating Emily and their relationship later becomes exclusive. Raj also has a Yorkshire Terrier named Cinnamon.
Well done! Really great final episode writing. The characters we have enjoyed for 12 seasons went on with their lives. . .but reached a happy place at that moment of time. Amy and Sheldon recognized for their brilliance. Penny and Leonard growing into a family. Bernadette and Howard being concerned about the children. Raj having someone fun to attend the ceremony with. Way to tie things up on a pleasant note.
Two nerdy physicists share an apartment and an unlikely friendship with their beautiful neighbor with whom one of them is infatuated. Like the universe after the big bang, the show's popularity expanded, thanks to breakout star Jim Parsons, along with the chemistry among the friends and the developing romance between Leonard and Penny. The addition of Melissa Rauch and Mayim Bialik in later seasons also enhanced the stories and relationships of the leads.
President Siebert charges Leonard with distributing some extra university funds in the form of a grant. Everyone begins sucking up to Leonard. Penny is impressed by Leonard's decisiveness but unimpressed when he cannot decide between Raj, Kripke and Dr. Lee (Maribeth Monroe), an ornithologist who works with crows. Leonard, realizing that people will be angry with him no matter who he gives the funds to, eventually awards the money to himself; many crows swarm his car afterwards. Meanwhile, a stressed out Bernadette starts hiding in Halley's playhouse after work so she can have time to herself. She is eventually joined by Penny and Amy. Howard reveals to Raj that he actually knows that Bernadette has been hiding out, but is keeping quiet about it so she can have her privacy and so he can use it to his advantage.
Kevin Sussman as Stuart Bloom (recurring seasons 2–5, 7, starring seasons 6, 8–12):[54] A mild-mannered, under-confident owner of a comic book store. A competent artist, Stuart is a graduate of the prestigious Rhode Island School of Design, and though he is socially awkward he possesses slightly better social skills. Stuart implies he is in financial trouble and that the comic book store now also is his home. He is later invited to join the guys' group while Howard is in space. Stuart gets a new job caring for Howard's mother later. After Mrs. Wolowitz's death, Stuart continues to live in her home, along with Howard and Bernadette, until he finds a place of his own.
The first and second pilots of The Big Bang Theory were directed by James Burrows, who did not continue with the show. The reworked second pilot led to a 13-episode order by CBS on May 14, 2007.[10] Prior to its airing on CBS, the pilot episode was distributed on iTunes free of charge. The show premiered on September 24, 2007, and was picked up for a full 22-episode season on October 19, 2007.[11] The show is filmed in front of a live audience,[12] and is produced by Warner Bros. Television and Chuck Lorre Productions.[13] Production was halted on November 6, 2007, due to the Writers Guild of America strike. Nearly three months later, on February 4, 2008, the series was temporarily replaced by a short-lived sitcom, Welcome to The Captain. The series returned on March 17, 2008, in an earlier time slot[14] and ultimately only 17 episodes were produced for the first season.[15][16]
The episode opens with a short montage of clips from the series' twelve seasons, then segues to Sheldon and Amy, who are up late waiting for a call from the Nobel Committee. Following a prank call from Kripke, they are told they've won the Nobel Prize in Physics for their super-asymmetry work. The attention from the media and the university bothers Sheldon. Amy is saddened by an unflattering picture of her in a news report, so Raj convinces her to get a makeover. She loves her new look but Sheldon demands she change it back. Leonard calls him out for being rude, but Sheldon flees when he sees Penny emerge from the newly repaired elevator. Sheldon and Penny go to the Cheesecake Factory and Penny tells Sheldon that change is the only constant thing in life. On a TV, they see Bernadette and Howard take credit as Sheldon and Amy's best friends. Raj and Leonard defend Amy, with Leonard accidentally breaking Sheldon's DNA molecule model in Apartment 4A. Penny convinces Sheldon to ride in the elevator.

Regina King reprised her role as Janine Davis in “The Retraction Reaction”. Bob Newhart returned as Arthur Jeffries in “The Proton Regeneration”. Dean Norris reprised his role as Colonel Williams in “The Tesla Recoil”. Brian Thomas Smith returned as Zack in “The Bitcoin Entanglement”. Brian George guest starred as Raj’s father, Dr. Koothrappali, in “The Confidence Erosion”. Joshua Malina reprised his role as President Siebert in “The Monetary Insufficiency”.


Two physicists from Chicago, Dr. Campbell and Dr. Pemberton, accidentally prove Sheldon and Amy's super-asymmetry theory. This puts them on track for a Nobel Prize, but Leonard points out they tend to go to the experimental scientists who prove a concept instead of theorists like Sheldon who come up with it. Meeting with them, they tell Sheldon they are willing to share the Prize but only three names can be on the submission, and they want to cut Amy out. Amy does not want to prevent Sheldon's lifelong dream, but he goes to President Seibert who agrees to fight for Amy on their behalf. Meanwhile, Bernadette's drug has been approved and she wants to promote Penny to lead the marketing team. Penny resists, knowing Bernadette's attitude at work and doubting her own inexperience to take the responsibility, but Bernadette uses reverse-psychology to get Penny to take the job. Penny mirrors Bernadette's commanding style to get the other employees in line, impressing Bernadette.

"The Locomotive Manipulation" is the first episode in which Sheldon initiates a kiss with Amy. Although initially done in a fit of sarcasm, he discovers that he enjoys the feeling. Consequently, Sheldon slowly starts to open up over the rest of the season, and starts a more intimate relationship with Amy. However, in the season finale, Sheldon leaves temporarily to cope with several changes and Amy becomes distraught. However, in "The Prom Equivalency", he hides in his room to avoid going to a mock prom reenactment with her. In the resulting stand-off, Amy is about to confess that she loves Sheldon, but he surprises her by saying that he loves her too. This prompts Amy to have a panic attack.


Sara Gilbert as Leslie Winkle (recurring season 1, starring season 2, guest seasons 3, 9):[47][48][49] A physicist who works in the same lab as Leonard. In appearance, she is essentially Leonard's female counterpart and has conflicting scientific theories with Sheldon. Leslie has casual sex with Leonard and later Howard. Gilbert was promoted to a main cast member during the second season but resumed guest star status because producers could not come up with enough material for the character.[47] Gilbert returned to The Big Bang Theory for its 200th episode.[50]
In the episode "The Launch Acceleration", Amy tries to use her "neurobiology bag of tricks" to increase the attraction between herself and Sheldon. In the final fifth-season episode "The Countdown Reflection", Sheldon takes Amy's hand as Howard is launched into space. In the sixth season first episode "The Date Night Variable", after a dinner in which Sheldon fails to live up to this expectation, Amy gives Sheldon an ultimatum that their relationship is over unless he tells her something from his heart. Amy accepts Sheldon's romantic speech even after learning that it is a line from the first Spider-Man movie. In "The Cooper/Kripke Inversion" Sheldon states that he has been working on his discomfort about physical contact and admits that "it's a possibility" that he could one day have sex with Amy. Amy is revealed to have similar feelings in "The Love Spell Potential". Sheldon explains that he never thought about intimacy with anyone before Amy.[82]

By season seven, Galecki, Parsons, and Cuoco were also receiving 0.25% of the series' back-end money. Before production began on the eighth season, the three plus Helberg and Nayyar, looked to renegotiate new contracts, with Galecki, Parsons, and Cuoco seeking around $1 million per episode, as well as more back-end money.[36] Contracts were signed in the beginning of August 2014, giving the three principal actors an estimated $1 million per episode for three years, with the possibility to extend for a fourth year. The deals also include larger pieces of the show, signing bonuses, production deals, and advances towards the back-end.[37] Helberg and Nayyar were also able to renegotiate their contracts, giving them a per-episode pay in the "mid-six-figure range", up from around $100,000 per episode they each received in years prior. The duo, who were looking to have salary parity with Parsons, Galecki, and Cuoco, signed their contracts after the studio and producers threatened to write the characters out of the series if a deal could not be reached before the start of production on season eight.[38] By season 10, Helberg and Nayyar reached the $1 million per episode parity with Parsons, Galecki, and Cuoco, due to a clause in their deals signed in 2014.[39]
Sheldon needs half a billion dollars to prove his latest concept of string theory, which the University cannot afford to fund. Crowdfunding and selling some of his most valuable comic books to Stuart give him a small start. When Raj mentions gambling in Las Vegas, Sheldon goes there but is caught calculating odds by security before he can make any bets. Meanwhile, Amy takes Penny and Bernadette shopping for her wedding dress. She loves an old-fashioned one that the other girls admit that they find ugly, though Penny assures Amy she can make her own decisions about her wedding. Sheldon, however, comes home and sees Amy in the dress and loves how she looks.
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